Deux-Sèvres, like other departments in France, is a part of a centralized system of government that is regulated by the national government in Paris. As a result, the department's economic policies are largely influenced by the policies of the French government. Agriculture is a significant part of the department's economy, and Deux-Sèvres is known for its production of wheat, corn, and sunflowers. The department is also home to a number of small and medium-sized enterprises, particularly in the food processing and manufacturing industries. However, the local economy has also been impacted by the global economic crisis, as well as the COVID-19 pandemic.

The department is actively involved in promoting economic development and job creation, with initiatives aimed at attracting new businesses and investments. The government of Deux-Sèvres provides a range of support services for entrepreneurs and start-ups, including business incubators and funding programs. The department also supports training and education programs to ensure that the local workforce has the necessary skills to compete in the global economy.

Overall, the government of Deux-Sèvres works closely with businesses and other stakeholders to promote economic growth and prosperity in the region, while also taking steps to ensure that the environment and natural resources are protected for future generations.